Welcome to FerrDb

NB: The database is undergoing regular maintenance and may be unstable. Do not hesitate to contact us for support if needed.

FerrDb is the world's first database that dedicates to ferroptosis regulators and ferroptosis-disease associations. There are two secondary categories of ferroptosis regulators: (1) genes and (2) substances. Gene regulators include driver, suppressor, marker, and unclassified regulator. Substances cover a wide range of chemical entities, including pure substances (e.g., iron, erastin) and mixtures (e.g., herbal extracts). Substance regulators include inducers and inhibitors. On the basis of this philosophy, FerrDb consists of seven independent curated data sets.

Driver

Genes that promote ferroptosis.

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Suppressor

Genes that prevent ferroptosis.

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Marker

Genes that indicate the occurrence of ferroptosis.

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Unclassified regulator

Genes whose role in ferroptosis is unclear.

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Inducer

Substances (e.g. compounds, ions, herbal extracts) that can cause ferroptosis.

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Inhibitor

Substances (e.g. compounds, ions, herbal extracts) that can restrict ferroptosis.

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Ferroptosis-disease association

Associations between ferroptosis and disease.

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