FerrDb is the world's first database that dedicates to ferroptosis regulators and ferroptosis-disease associations. There are two categories of ferroptosis regulators: (1) genes and (2) substances. Gene regulators include driver, suppressor, marker, and unclassified gene. Substances cover a wide range of chemical entities, including pure substances (e.g., iron, erastin) and mixtures (e.g., herbal extracts). Substance regulators include inducer and inhibitor. On the basis of this philosophy, FerrDb consists of seven independent data sets.