RNAdt is a web-based tutorial and data portal for HTS-associated RNA structure probing methods.
Users can use RNAdt to learn to implement RNA structure probing experiments with easy
because the workflow of each method from its original publication is provided. For
users who are interested in learning to analyze RNA structurome data, RNAdt can be
used as a data portal to reach existing HTS data sets.
Of note, we may not include the complete list of RNA structure probing methods due to imperfect search and filtering strategies. We apologize to authors whose state-of-the-art methods are not included in this version of RNAdt. RNAdt promises to provide free and long-term service. In the future, RNAdt will be continuously updated and more RNA structure probing methods will be added in. RNAdt is expected to be a valuable resource to get profound insights into the RNA biology.
The source code of RNAdt has been released on GitHub. You were appreciated if you could make a contribution to this project.
HTS: High-throughput sequencing.
_NA_: Not Available owing to no data from the original source, or Not Applicable.
RT: Reverse Transcription.
|Method||The name of the RNA structure probing method.|
|Year||The year when this method was published.|
|Name||The full name of this method.|
|Publication||The title of the article in which this method was published.|
|Published by||The authors of the article in which this method was published.|
|Publication abstract||The abstract of the article in which this method was published.|
|Publication data||The HTS data alongside the article in which this method was published.|
|Publication doi||The DOI of the article in which this method was published.|
|Probe||The probe(s) this method uses.|
|Probe class||What class the probe(s) belongs to.|
|Probe target||Which nucleobase or moiety the probe targets.|
|Target region||Which part of the RNA strand the probe targets.|
|Readout||The method used to read structural signal (e.g. reactivity).|
|Scale||The scale at which this method assesses RNA structure.|
|Structure inferred||The type of the probed high-level RNA structure.|
|Validated by||The RNA used to validate this method.|
|Validated in||The organism or biological system used to validate this method.|
|Workflow||The schematic workflow of this method from its original publication.|
|Figure reuse license||The license of permission granted to RNAdt to use the original figure from its copyright holder.|